SCHEMBL7684160

SCHEMBL7684160

CCOC(=O)CC[C@H]1CCCNC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
CHRNB2 P17787 2/20 0.44
CHRNB4 P30926 2/20 0.44
CHRNA3 P32297 2/20 0.44
CHRNA4 P43681 2/20 0.44
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 2/20 0.40
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40
CPN1 P15169 1/20 0.40
CPB2 Q96IY4 1/20 0.40
NAAA Q02083 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
ROCK2 O75116 1/20 0.39
ACP1 P24666 2/20 0.38
KLK7 P49862 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
ATM Q13315 1/20 0.38
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3952133 1.00 KMT2A (0.50) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL1410339 0.90 SLC6A1 (0.44) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL4523217 0.84 SLC6A1 (0.44) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL2446601 0.84 SLC6A1 (0.44) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL567871 0.84 SLC6A1 (0.44) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL1037020 0.84 KMT2A (0.52) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL24393166 0.83 ALDH1A1 (0.43) KMT2ATDP1ALDH1A1USP2ALOX15
Hydrochloric Acid SCHEMBL27859719 0.83 KMT2A (0.51) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
Hydrochloric Acid SCHEMBL6958695 0.83 EPHX1 (0.43) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4
Hydrochloric Acid SCHEMBL31041002 0.83 EPHX1 (0.43) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020007071-A1 Benzimidzolyl neuropeptide Y receptor antagonists BRITTON THOMAS CHARLES (US) 2002-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007071-A1 Benzimidzolyl neuropeptide Y receptor antagonists NPY1R, NPY2R, NPY5R KMT2A 1885/4885CHRNB2 534/4885CHRNB4 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.