SCHEMBL4523217

SCHEMBL4523217

CCOC(=O)C[C@H]1CCCNC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 4/20 0.44
SLC6A11 P48066 3/20 0.44
SLC6A13 Q9NSD5 3/20 0.44
GABRA5 P31644 2/20 0.44
GABRB2 P47870 2/20 0.44
SLC6A12 P48065 2/20 0.44
EPHX1 P07099 1/20 0.44
GABRA1 P14867 1/20 0.44
GABRR1 P24046 1/20 0.44
GABRA4 P48169 1/20 0.44
CPN1 P15169 1/20 0.42
CPB2 Q96IY4 1/20 0.42
POLB P06746 1/20 0.41
KDM1A O60341 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446601 1.00 SLC6A1 (0.44) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
SCHEMBL567871 1.00 SLC6A1 (0.44) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL15549279 0.98 EPHX1 (0.43) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL6958695 0.98 EPHX1 (0.43) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL31041002 0.98 EPHX1 (0.43) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL1876593 0.94 SLC6A1 (0.42) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
SCHEMBL15930224 0.90 SLC6A1 (0.56) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL30455767 0.88 SLC6A1 (0.55) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL6102502 0.88 SLC6A1 (0.55) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
SCHEMBL8414225 0.87 POLB (0.41) SLC6A1SLC6A11SLC6A13GABRA5GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230140-A1 NOVEL TRIAZOLE-PYRIDINE SUBSTITUTED PYRROLIDINYL AND TETRAHYDRO-2H-PYRANYL ACETIC ACID COMPOUNDS AS LPA ANTAGONISTS VIVA STAR BIOSCIENCES (SUZHOU) CO., LTD. (CN) 2025-07-17 US disclosed
EP-4330249-A1 NOVEL TRIAZOLE-PYRIDINE SUBSTITUTED PYRROLIDINYL AND TETRAHYDRO-2H-PYRANYL ACETIC ACID COMPOUNDS AS LPA ANTAGONISTS Viva Star Biosciences (Suzhou) Co., Ltd. (CN) 2024-03-06 EP disclosed
CN-117447450-A Triazole compounds and their use as LPAR1 antagonists 武汉人福创新药物研发中心有限公司 2024-01-26 CN disclosed
EP-4196220-A1 TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS Viva Star Biosciences Limited (HK) 2023-06-21 EP disclosed
WO-2022232459-A1 NOVEL TRIAZOLE-PYRIDINE SUBSTITUTED PYRROLIDINYL AND TETRAHYDRO-2H-PYRANYL ACETIC ACID COMPOUNDS AS LPA ANTAGONISTS VIVA STAR BIOSCIENCES (SUZHOU) CO., LTD. (CN) 2022-11-03 WO disclosed
US-20220127247-A1 N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE NOVARTIS INSTITUTE FOR FUNCTIONAL GENOMICS, INC., DBA THE GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION (GNF) 2022-04-28 US disclosed
WO-2022034568-A1 TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS VIVA STAR BIOSCIENCES LIMITED (CN) 2022-02-17 WO disclosed
CN-113423702-A N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use in the treatment of disease 诺华股份有限公司 2021-09-21 CN disclosed
EP-2879673-B1 1,5,6-substituted naphthalene derivatives as sphingosine 1 phosphate (S1P) receptor and/or autotaxin (ATX) modulators for treating inflammatory and autoimmune disorders BIOGEN MA INC (US) 2018-07-25 EP disclosed
US-10017506-B2 ATX modulating agents BIOGEN MA INC. (US) 2018-07-10 US disclosed
WO-2007090579-A2 SUBSTITUTED QUINOLONES III AICURIS GMBH & CO. KG (DE) 2007-08-16 WO disclosed
US-20070129397-A1 Ester derivatives MSD K.K. (JP) 2007-06-07 US disclosed
US-7192969-B2 Ester derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-03-20 US disclosed
US-20050065211-A1 Ester derivatives MSD K.K. (JP) 2005-03-24 US disclosed
US-6846835-B2 Treating chronic obstructive pulmonary disease, chronic bronchitis, asthma, chronic respiratory tract obstruction, fibroid lung, pulmonary emphysema or rhinitis BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-01-25 US disclosed
US-20030191316-A1 Ester derivatives MSD K.K. (JP) 2003-10-09 US disclosed
EP-1302458-A1 ESTER DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2003-04-16 EP disclosed
EP-0983269-A4 PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS LILLY CO ELI (US) 2001-06-27 EP disclosed
EP-0983269-A1 PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 2000-03-08 EP disclosed
WO-1998054179-A1 PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 1998-12-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129397-A1 Ester derivatives CHRM3, CHRM2, CHRM1 SLC6A1 2681/4885SLC6A11 2701/4885SLC6A13 3100/4885
US-20030191316-A1 Ester derivatives CHRM3, CHRM2, CHRM1 SLC6A1 2737/4885SLC6A11 3324/4885SLC6A13 3561/4885
US-20220127247-A1 N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE CFTR, P2RY1, P2RX5 SLC6A1 1017/4885SLC6A11 1014/4885SLC6A13 1565/4885
US-20050065211-A1 Ester derivatives CHRM3, CHRM2, CHRM1 SLC6A1 2756/4885SLC6A11 2796/4885SLC6A13 3179/4885
US-20250230140-A1 NOVEL TRIAZOLE-PYRIDINE SUBSTITUTED PYRROLIDINYL AND TETRAHYDRO-2H-PYRANYL ACETIC ACID COMPOUNDS AS LPA ANTAGONISTS LPAR3, LPAR2, LPAR1 SLC6A1 2845/4885SLC6A11 2062/4885SLC6A13 2415/4885
US-10017506-B2 ATX modulating agents ENPP2, ATXN10, ATXN2 SLC6A1 4062/4885SLC6A11 3834/4885SLC6A13 4440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.