SCHEMBL7684374

SCHEMBL7684374

CC(Cl)OCCOc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.52
PKM P14618 2/20 0.47
HTR1B P28222 2/20 0.47
LMNA P02545 1/20 0.47
HTR1D P28221 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
ALDH1A1 P00352 1/20 0.47
RECQL P46063 1/20 0.47
LTA4H P09960 2/20 0.46
SIGMAR1 Q99720 1/20 0.45
CHRNB2 P17787 2/20 0.44
CHRNB4 P30926 2/20 0.44
CHRNA3 P32297 2/20 0.44
CHRNA7 P36544 2/20 0.44
CHRNA4 P43681 2/20 0.44
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
MAOA P21397 1/20 0.43
PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6564405 0.83 KCNA3 (0.56) KCNA3PKMHTR1BLMNAHTR1D
SCHEMBL11487020 0.82 DRD4 (0.45) SIGMAR1RAB9A
SCHEMBL15277305 0.80 ALDH1A1 (0.44) KCNA3PKMHTR1BLMNAHTR1D
SCHEMBL3169811 0.80 LMNA (0.57) KCNA3PKMHTR1BLMNAHTR1D
SCHEMBL11661699 0.80 KCNA3 (0.52) KCNA3PKMHTR1BLMNAHTR1D
SCHEMBL4459036 0.80 KCNA3 (0.52) KCNA3PKMHTR1BLMNAHTR1D
SCHEMBL10228463 0.80 KCNA3 (0.52) KCNA3PKMHTR1BLMNAHTR1D
SCHEMBL14685192 0.79 KCNA3 (0.47) KCNA3PKMHTR1BLMNAHTR1D
SCHEMBL3161500 0.79 KCNA3 (0.61) KCNA3PKMHTR1BHTR1DTAAR1
SCHEMBL775134 0.78 KCNA3 (0.50) KCNA3PKMHTR1BLMNAHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645531-A Preparation method of p-tert-octyl phenoxy ethoxy ethyl chloride 扬州市普林斯医药科技有限公司 2024-03-05 CN disclosed
US-6455538-B1 SODIUM CHANNEL MODULATORS; BRAIN AND NERVOUS SYSTEM DISORDERS BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-09-24 US disclosed
CN-1163885-A Bactericide modified quaternary ammonium salt and preparation method thereof NANJING CHEMICAL UNIV (CN) 1997-11-05 CN disclosed