Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CCR2 | P41597 | 4/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480710 | 0.91 | ALDH1A1 (0.57) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL29937398 | 0.89 | MTNR1A (0.65) | ALDH1A1CYP1A2POLBMTNR1AMTNR1B | |
| SCHEMBL6701625 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL2476665 | 0.86 | CCR2 (0.60) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| Hydrochloric Acid SCHEMBL9085791 | 0.84 | ALDH1A1 (0.59) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL7682421 | 0.84 | MTNR1A (0.51) | ALDH1A1CYP1A2POLBCCR2MTNR1A | |
| SCHEMBL11681610 | 0.83 | KDM4E (0.62) | ALDH1A1CYP1A2POLBTSHRHTT | |
| SCHEMBL29750342 | 0.83 | ALDH1A1 (0.64) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL7894118 | 0.83 | ALDH1A1 (0.64) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL700800 | 0.81 | ALDH1A1 (0.69) | ALDH1A1CYP1A2POLBCCR2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |