SCHEMBL7684689

SCHEMBL7684689

C=C(C)C(=O)OC(C)(COOC(C)(C)c1ccccc1)OC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
ALDH1A1 P00352 4/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.33
ELANE P08246 1/20 0.33
HTT P42858 1/20 0.32
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763282 0.87 CYP2D6 (0.36) HIF1ASMN1; SMN2
SCHEMBL8762576 0.81 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL8368618 0.78 MAPK1 (0.41) MAPK1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL3393201 0.77 ALDH1A1 (0.48) MAPK1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL7691605 0.77
SCHEMBL9723227 0.76
Ethane SCHEMBL28621749 0.76 ALDH1A1 (0.47) MAPK1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL7691705 0.75 LMNA (0.31) TSHR
SCHEMBL16016805 0.74 MAPK1 (0.53) MAPK1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL27861873 0.73 MAPK1 (0.57) MAPK1CYP2C19HIF1AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531978-B Methacrylic resin composition 株式会社可乐丽 2020-11-03 CN disclosed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-6335401-B1 ADHESION PRIMER ATOFINA (FR) 2002-01-01 US disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0608856-B1 Graft precursor and process for producing grafted aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1997-07-09 EP disclosed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP disclosed
EP-0435340-B1 Thermoplastic resin compositions NIPPON PETROCHEMICALS CO LTD (JP) 1996-05-01 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438108-A Melt-kneading a mixture of aromatic polycarbonate resin and vinylic copolymer containing active oxygen; optical distortion reduction MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-08-01 US disclosed
EP-0361400-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-04-04 EP disclosed
US-4879347-A ETHYLENE POLYMER, VINYL MONOMER, RADICAL POLYMERIZABLE ORGANIC PEROXIDE, FREE RADICAL CATALYST, COPOLYMERIZATION NIPPON OIL AND FATS CO., LTD. (JP) 1989-11-07 US disclosed
US-4877841-A GRAFT POLYMER OF POLYETHYLENE, UNSATURATED MONOMER AND AN UNSATURATED PEROXYCARBONATE; SOLUBILIZERS FOR POLYMER BLENDS NIPPON OIL AND FATS CO., LTD. (JP) 1989-10-31 US disclosed
EP-0338303-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-10-25 EP disclosed
EP-0314188-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0307802-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-22 EP disclosed
EP-0304039-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304041-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0295706-A2 Thermoplastic resin composition and method for preparing the same Nippon Petrochemicals Co., Ltd. (JP) 1988-12-21 EP disclosed
EP-0289933-A2 Graft polymerization precurser and method manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed