Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488674 | 0.75 | CLK1 (0.49) | BCHEACHEKDM4EMAPTNPC1 | |
| SCHEMBL25455606 | 0.73 | CCR2 (0.36) | HTTMEN1KMT2AKDM4EMAPT | |
| SCHEMBL9054795 | 0.70 | PTK2 (0.48) | PTK2PIK3CAPIK3CGPIK3CBKMT2A | |
| SCHEMBL24181811 | 0.69 | PTK2 (0.41) | PTK2MEN1KMT2AKDM4EGRM5 | |
| SCHEMBL24575920 | 0.68 | CCR2 (0.36) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1534064 | 0.66 | PLAU (0.42) | PTK2ACHEMEN1KMT2APLAU | |
| SCHEMBL3107273 | 0.66 | ALDH1A1 (0.38) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL1120994 | 0.65 | PIK3CG (0.51) | BCHEACHEPIK3CAPIK3CGPIK3CB | |
| SCHEMBL1984433 | 0.65 | KDR (0.55) | BCHEACHEPIK3CAPIK3CG | |
| SCHEMBL7687760 | 0.65 | NPC1 (0.39) | PIK3CAPIK3CGPIK3CBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |