Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685050 | 0.81 | ALDH1A1 (0.44) | IDO1BCHEMTNR1AMTNR1BACHE | |
| SCHEMBL7684805 | 0.79 | IDO1 (0.39) | IDO1CYP19A1MTNR1AMTNR1BDRD3 | |
| SCHEMBL7685128 | 0.75 | BCHE (0.45) | IDO1BCHEMTNR1AMTNR1BACHE | |
| SCHEMBL2741074 | 0.74 | IDO1 (0.47) | IDO1CYP19A1DRD3ADRA1DADRA1A | |
| SCHEMBL7709416 | 0.73 | BCHE (0.43) | IDO1BCHEMTNR1AMTNR1BACHE | |
| SCHEMBL14073847 | 0.71 | GLA (0.42) | IDO1BCHEACHE | |
| SCHEMBL10447562 | 0.71 | IDO1 (0.44) | IDO1BCHECYP19A1DRD3ADRA2A | |
| SCHEMBL23675571 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL23675573 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL19540992 | 0.71 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |