Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | PTGIR | P43119 | 4/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685077 | 0.79 | IDO1 (0.41) | IDO1CYP19A1MTNR1AMTNR1BADRA1D | |
| SCHEMBL10447562 | 0.76 | IDO1 (0.44) | IDO1CYP19A1DRD3ADRA2A | |
| SCHEMBL19645163 | 0.75 | IDO1 (0.44) | IDO1MTNR1AMTNR1BDRD3MEN1 | |
| SCHEMBL7680750 | 0.73 | HTR6 (0.42) | IDO1MTNR1AMTNR1BADRA1A | |
| SCHEMBL12851335 | 0.71 | HTR2A (0.41) | IDO1CYP19A1ADRA1DADRA1AADRA1B | |
| SCHEMBL7676484 | 0.71 | ALDH1A1 (0.41) | IDO1CYP19A1ADRA1DADRA1AADRA1B | |
| SCHEMBL7685050 | 0.71 | ALDH1A1 (0.44) | IDO1MTNR1AMTNR1B | |
| SCHEMBL2741074 | 0.71 | IDO1 (0.47) | IDO1CYP19A1ADRA1DADRA1AADRA1B | |
| SCHEMBL18785885 | 0.69 | MTNR1A (0.42) | IDO1MTNR1AMTNR1BADRA1DADRA1A | |
| Catechol SCHEMBL10642410 | 0.67 | MAPT (0.46) | IDO1MEN1GAAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |