Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709416 | 0.83 | BCHE (0.43) | BCHEMTNR1AMTNR1BGAAKDM4E | |
| SCHEMBL7685050 | 0.82 | ALDH1A1 (0.44) | BCHEMTNR1AMTNR1BIDO1ACHE | |
| SCHEMBL14073847 | 0.82 | GLA (0.42) | BCHEGAAIDO1ACHEFFAR1 | |
| SCHEMBL2246761 | 0.76 | GAA (0.47) | GAAALDH1A1 | |
| SCHEMBL17013377 | 0.76 | MTNR1A (0.46) | BCHEMTNR1AMTNR1B | |
| SCHEMBL13351529 | 0.75 | MTNR1A (0.47) | BCHEMTNR1AMTNR1BIDO1FFAR1 | |
| SCHEMBL7685077 | 0.75 | IDO1 (0.41) | BCHEMTNR1AMTNR1BIDO1ACHE | |
| SCHEMBL10531104 | 0.73 | NOTUM (0.48) | GAAIDO1NR1D1ALDH1A1 | |
| SCHEMBL13878656 | 0.73 | LMNA (0.47) | GAAALDH1A1 | |
| SCHEMBL256681 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423058-B2 | Inhibitors of hepatitis C virus NS3 protease | SCHERING CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |