Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031664 | 0.87 | ALDH1A1 (0.43) | AOC3SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL28396867 | 0.86 | AOC3 (0.54) | AOC3SMN1; SMN2TSHRHTTL3MBTL1 | |
| SCHEMBL8031654 | 0.84 | ALDH1A1 (0.48) | SMN1; SMN2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL29622963 | 0.83 | AOC3 (0.67) | AOC3SMN1; SMN2TSHRHTTL3MBTL1 | |
| SCHEMBL29622962 | 0.83 | AOC3 (0.67) | AOC3SMN1; SMN2TSHRHTTL3MBTL1 | |
| SCHEMBL2968894 | 0.82 | MEN1 (0.63) | SMN1; SMN2TSHRHTTL3MBTL1MEN1 | |
| SCHEMBL9815410 | 0.81 | RAB9A (0.53) | AOC3TSHRMEN1KMT2AMAPT | |
| SCHEMBL5537937 | 0.80 | AOC3 (0.49) | AOC3SMN1; SMN2TSHRHTTL3MBTL1 | |
| SCHEMBL5537940 | 0.80 | AOC3 (0.49) | AOC3SMN1; SMN2TSHRHTTL3MBTL1 | |
| SCHEMBL11116153 | 0.80 | SMN1; SMN2 (0.59) | AOC3SMN1; SMN2TSHRHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016273-A1 | ISOQUINOLINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USES OF ISOQUINOLINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION | 拜西欧斯（北京）生物技术有限公司 | 2025-01-23 | — | — | WO | disclosed |
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6140051-A | USE IN THE FIELD OF BIOLOGICAL ASSAYS | PROMEGA BIOSCIENCES, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-1000042-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | Promega Biosciences, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-2000004007-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999003849-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 1999-01-28 | — | — | WO | disclosed |
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010506-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-20 | — | — | WO | disclosed |
| US-5225431-A | Treatment of migraine | BURROUGHS WELLCOME CO. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0313397-B1 | THERAPEUTIC HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0313397-A1 | Therapeutic heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-04-26 | — | — | EP | disclosed |