Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245477 | 0.80 | PIM1 (0.42) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL29786760 | 0.80 | KMT2A (0.61) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL5517816 | 0.80 | ALDH1A1 (0.48) | LMNATDP1THRBALDH1A1TSHR | |
| SCHEMBL982388 | 0.80 | KMT2A (0.61) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL5663780 | 0.74 | ERN1 (0.43) | MEN1KMT2ATDP1BLMALDH1A1 | |
| SCHEMBL536090 | 0.74 | LMNA (0.55) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL9989131 | 0.73 | TNKS (0.42) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL8468137 | 0.72 | ALDH1A1 (0.38) | TDP1ALDH1A1TSHRNPSR1KIF11 | |
| SCHEMBL2184850 | 0.72 | CYP1A2 (0.59) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL1176809 | 0.72 | PABPC1 (0.49) | TDP1THRBALDH1A1TSHRPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359148-B1 | FOR POLYMER, LUBRICANTS; HEAT, OXIDATION RESISTANCE, PHOTOSTABILITY | NESVADBA PETER (CH) | 2002-03-19 | — | — | US | disclosed |
| US-6346630-B1 | 3-Arylbenzofuranones as stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-12 | — | — | US | disclosed |
| EP-0648765-B1 | Process for the production of 3-arylbenzofuranones | CIBA SC HOLDING AG (CH) | 2000-07-12 | — | — | EP | disclosed |
| US-5807505-A | HEAT AND OXIDATION RESISTANCE, PHOTOSTABILITY OF POLYMERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| US-5773631-A | PROTECTION OF POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT INDUCED DEGRDATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| US-5693829-A | PROTECT AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| US-5607624-A | Process for the preparation of 3-arylbenzofuranones | CIBA-GEIGY CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| US-5516920-A | POLYMER STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0648765-A1 | Process for the production of 3-arylbenzofuranones | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |