Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677586 | 0.92 | HTT (0.41) | PTGS2S1PR4PDE4APDE4BPDE4C | |
| SCHEMBL7676352 | 0.91 | PTGS2 (0.37) | PTGS2S1PR4PDE4APDE4BPDE4C | |
| SCHEMBL7683047 | 0.90 | PDE4A (0.38) | PTGS2S1PR4PDE4APDE4BPDE4C | |
| SCHEMBL7686030 | 0.90 | PTGS2 (0.35) | PTGS2S1PR4PDE4APDE4BPDE4C | |
| SCHEMBL7681363 | 0.86 | PTGS2 (0.41) | PTGS2S1PR4PDE4APDE4BPDE4C | |
| SCHEMBL7685456 | 0.85 | TSHR (0.39) | S1PR4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL678914 | 0.84 | P2RX7 (0.38) | S1PR4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7676322 | 0.84 | HTT (0.40) | PTGS2S1PR4PDE4APDE4BPDE4C | |
| SCHEMBL7684085 | 0.83 | PDE4D (0.40) | PTGS2S1PR4PDE4APDE4BPDE4C | |
| SCHEMBL7680208 | 0.82 | PDE4A (0.38) | PTGS2S1PR4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |