Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 8/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813338 | 0.85 | F10 (0.42) | F10 | |
| SCHEMBL7451641 | 0.85 | GPR55 (0.47) | GPR55F10CA1CA2CA12 | |
| SCHEMBL14615719 | 0.75 | GPR55 (0.59) | GPR55CA1CA2CA12CA9 | |
| SCHEMBL7685986 | 0.75 | F10 (0.59) | F10 | |
| SCHEMBL7681921 | 0.74 | F10 (0.48) | GPR55F10CA1CA2 | |
| SCHEMBL7813337 | 0.72 | F10 (0.58) | F10 | |
| SCHEMBL394902 | 0.68 | CA1 (0.59) | GPR55CA1CA2CA12CA9 | |
| SCHEMBL3633256 | 0.68 | CA1 (0.78) | CA1CA2CA12CA9LMNA | |
| SCHEMBL890942 | 0.67 | GPR55 (0.60) | GPR55CA1CA2CA12CA9 | |
| SCHEMBL891005 | 0.67 | MAPT (0.53) | GPR55CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1159264-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |