Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685986 | 0.87 | F10 (0.59) | F10F2PRSS1KCNH2 | |
| SCHEMBL7813338 | 0.75 | F10 (0.42) | F10F2PRSS1KCNH2 | |
| SCHEMBL7451638 | 0.73 | F10 (0.59) | F10F2PRSS1KCNH2 | |
| SCHEMBL7688216 | 0.73 | F10 (0.59) | F10F2PRSS1KCNH2 | |
| SCHEMBL7690626 | 0.73 | F10 (1.00) | F10F2PRSS1KCNH2 | |
| SCHEMBL7685987 | 0.72 | GPR55 (0.47) | F10 | |
| SCHEMBL7684142 | 0.69 | F10 (1.00) | F10F2PRSS1KCNH2 | |
| SCHEMBL7684143 | 0.69 | F10 (1.00) | F10F2PRSS1KCNH2 | |
| SCHEMBL7688293 | 0.68 | F10 (1.00) | F10F2PRSS1KCNH2 | |
| SCHEMBL7690621 | 0.68 | F10 (1.00) | F10F2PRSS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159264-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |