Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.60 |
| ▸ | TUBB | P07437 | 7/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686393 | 1.00 | NPC1 (0.61) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL7287844 | 0.86 | RAB9A (0.54) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL7287849 | 0.86 | RAB9A (0.54) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL29660212 | 0.76 | NPC1 (1.00) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL537904 | 0.76 | NPC1 (1.00) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL537905 | 0.76 | NPC1 (1.00) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL1508835 | 0.75 | TUBB4A (1.00) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL1508832 | 0.75 | TUBB4A (1.00) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| (Z)-1,2-Diphenylethene SCHEMBL4393598 | 0.74 | ALDH1A1 (0.67) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| (Z)-1,2-Diphenylethene SCHEMBL4393600 | 0.74 | ALDH1A1 (0.67) | NPC1RAB9AKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |