Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 14/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 13/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 13/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669646 | 1.00 | ADRA1A (0.42) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6686591 | 0.82 | ADRA1A (0.50) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7638902 | 0.82 | ADRA1A (0.50) | ADRA1AADRA1DADRA1B | |
| SCHEMBL5661329 | 0.80 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL8004288 | 0.80 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL7928701 | 0.80 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL5662048 | 0.78 | ADRA1A (0.51) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7082388 | 0.74 | CTDSP1 (0.58) | ADRA1AADRA1DADRA1B | |
| SCHEMBL6645152 | 0.74 | CTDSP1 (0.58) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7082385 | 0.74 | CTDSP1 (0.58) | ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339090-B1 | FOR THERAPY OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2002-01-15 | — | — | US | claimed |