SCHEMBL7686448

SCHEMBL7686448

NC(=O)COc1nccs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.37
NOS1 P29475 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TP53 P04637 2/20 0.36
HPGD P15428 2/20 0.36
THRB P10828 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
PKM P14618 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
TBXAS1 P24557 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
ALOX15 P16050 1/20 0.35
POLB P06746 1/20 0.34
BLM P54132 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5086027 0.76
SCHEMBL11624815 0.75 ALDH1A1 (0.49) ALDH1A1HSD17B10NPC1RAB9ASMN1; SMN2
SCHEMBL5756337 0.74 MEN1 (0.38) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL9212257 0.73 ALDH1A1 (0.39) ALDH1A1TSHRNOS1HSD17B10NPC1
SCHEMBL28140898 0.72
SCHEMBL4755861 0.72 ALDH1A1 (0.38) ALDH1A1TSHRNOS1HSD17B10NPC1
SCHEMBL10639497 0.72 POLB (0.36) ALDH1A1TSHRKDM4EHTTL3MBTL1
SCHEMBL7476605 0.72 LOXL2 (0.53) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL27852103 0.71 ALDH1A1 (0.43) ALDH1A1TSHRNOS1HSD17B10NPC1
SCHEMBL27478065 0.71 ALDH1A1 (0.43) ALDH1A1TSHRNOS1HSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929743-A Novel 4,5-disubstituted 1,3-thiazol-2-yloxyacetamide herbicides BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US claimed
EP-0195237-B1 4,5-SUBSTITUTED-1,3-THIAZOL-2-YLOXYACETAMIDE BAYER AG (DE) 1988-11-02 EP claimed
EP-0195237-A1 4,5-Substituted-1,3-thiazol-2-yloxyacetamide BAYER AG (DE) 1986-09-24 EP claimed
JP-1026504-A None JP disclosed
US-6339042-B1 FOR COMBATING UNDESIRED PLANT GROWTH AMERICAN CYANAMID CO. 2002-01-15 US disclosed
EP-1047679-A1 HERBICIDAL N-ALKENYL HETEROARYLYLOXYACETAMIDES AMERICAN CYANAMID COMPANY (US) 2000-11-02 EP disclosed
WO-1999025702-A1 HERBICIDAL N-ALKENYL HETEROARYLYLOXYACETAMIDES AMERICAN CYANAMID COMPANY (US) 1999-05-27 WO disclosed
US-5068343-A Fungicides for plants BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
US-4929743-A Novel 4,5-disubstituted 1,3-thiazol-2-yloxyacetamide herbicides BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
US-4929743-A Novel 4,5-disubstituted 1,3-thiazol-2-yloxyacetamide herbicides BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
US-4929743-A Novel 4,5-disubstituted 1,3-thiazol-2-yloxyacetamide herbicides BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0195237-A1 4,5-Substituted-1,3-thiazol-2-yloxyacetamide BAYER AG (DE) 1986-09-24 EP disclosed
EP-0195237-A1 4,5-Substituted-1,3-thiazol-2-yloxyacetamide BAYER AG (DE) 1986-09-24 EP disclosed
EP-0195237-A1 4,5-Substituted-1,3-thiazol-2-yloxyacetamide BAYER AG (DE) 1986-09-24 EP disclosed
EP-0192148-A1 2,4-Dichlorothiazole derivatives and process for their preparation BAYER AG (DE) 1986-08-27 EP disclosed
US-4555577-A 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed
US-4555577-A 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed
EP-0115811-A2 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation BAYER AG (DE) 1984-08-15 EP disclosed
EP-0115811-A2 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation BAYER AG (DE) 1984-08-15 EP disclosed
JP-S06426504-A 0001-01-01 JP disclosed