⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212257 | 0.84 | ALDH1A1 (0.39) | — | |
| SCHEMBL28140898 | 0.83 | — | — | |
| SCHEMBL27852103 | 0.83 | ALDH1A1 (0.43) | — | |
| SCHEMBL27478065 | 0.83 | ALDH1A1 (0.43) | — | |
| SCHEMBL3559527 | 0.79 | — | — | |
| SCHEMBL3074508 | 0.79 | — | — | |
| SCHEMBL1633629 | 0.79 | — | — | |
| SCHEMBL1219078 | 0.79 | PKM (0.38) | — | |
| SCHEMBL4755861 | 0.79 | ALDH1A1 (0.38) | — | |
| SCHEMBL27979962 | 0.79 | L3MBTL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518858-A | Substituted benzothiazole diaryl urea compounds, and preparation method and medical application thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-03-22 | — | — | CN | claimed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | claimed |
| US-12486289-B2 | Tricyclic compounds as glycogen synthase kinase 3 (GSK3) inhibitors and uses thereof | THE BROAD INSTITUTE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| EP-4583870-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | Mito Biopharma, LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-119638687-A | Aromatic heterocyclic pyrrolidones and uses thereof | 杭州百新生物医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | disclosed |
| CN-116670136-A | Tetracyclic compound and medical application thereof | 正大天晴药业集团股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110958882-B | Tricyclic compounds as glycogen synthase kinase 3 (GSK 3) inhibitors and uses thereof | 布罗德研究所股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115201485-A | Methods of measuring KRAS protein inhibition | 百济神州(北京)生物科技有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-20220112216-A1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2022-04-14 | — | — | US | disclosed |
| EP-1601685-A1 | HEPATITIS C INHIBITING COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2005-12-07 | — | — | EP | disclosed |
| US-6919423-B2 | Hepatitis C inhibitor compound | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2005-07-19 | — | — | US | disclosed |
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | MITSUI CHEMICALS, INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1489073-A1 | PROCESS FORPREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES | MITSUI CHEMICALS, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
| WO-2004101605-A1 | HEPATITIS C INHIBITING COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |
| US-20040229818-A1 | Hepatitis C inhibitor compound | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-18 | — | — | US | disclosed |
| CN-1374955-A | Oxazole and thiazole derivatives as antidiabetic and antiobesity agents | BRISTOL MYERS SQUIBB CO (US) | 2002-10-16 | — | — | CN | disclosed |
| US-4987196-A | FROM NATURAL RUBBER LATEX | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-3825552-A | THIAZOLE CARBAMATE PESTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 1974-07-23 | — | — | US | disclosed |