Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686433 | 0.84 | MAPT (0.44) | NOD2NOD1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7683727 | 0.80 | NOD2 (0.46) | NOD2NOD1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7686577 | 0.76 | NOD2 (0.49) | NOD2NOD1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1553259 | 0.74 | SRD5A2 (0.58) | KMT2AMEN1L3MBTL1LMNASRD5A2 | |
| SCHEMBL85958 | 0.72 | SRD5A2 (0.51) | NOD2NOD1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7684727 | 0.72 | F10 (0.46) | NOD2NOD1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12392918 | 0.72 | SRD5A2 (0.53) | NOD2NOD1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7682416 | 0.70 | F10 (0.44) | NOD2NOD1KMT2AMEN1TDP1 | |
| SCHEMBL11529770 | 0.69 | MAPT (0.67) | NOD2NOD1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12930104 | 0.69 | NOD2 (0.67) | NOD2NOD1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |