Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686006 | 0.87 | MCL1 (0.46) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7686573 | 0.80 | NOD2 (0.44) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8689957 | 0.77 | SMN1; SMN2 (0.54) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7682416 | 0.77 | F10 (0.44) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22258127 | 0.74 | MCL1 (0.60) | NOD2NOD1KMT2ATDP1F10 | |
| SCHEMBL5794123 | 0.74 | NOD2 (0.57) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL29463237 | 0.74 | NOD2 (0.57) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11158786 | 0.74 | CNR2 (0.45) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2460494 | 0.72 | NOD2 (0.56) | NOD2NOD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8689867 | 0.72 | KDM4E (0.54) | NOD2NOD1KMT2AMEN1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |