Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684555 | 0.83 | MCL1 (0.53) | KMT2AMEN1CNR2CCR2POLB | |
| SCHEMBL22258127 | 0.78 | MCL1 (0.60) | F10F2KMT2ANOD2NOD1 | |
| SCHEMBL7682048 | 0.77 | KMT2A (0.57) | F10F2KMT2AMEN1NOD2 | |
| SCHEMBL7683727 | 0.77 | NOD2 (0.46) | F10F2KMT2AMEN1NOD2 | |
| SCHEMBL7682421 | 0.75 | MTNR1A (0.51) | F10F2KMT2AMEN1NOD2 | |
| SCHEMBL19362902 | 0.75 | KMT2A (0.46) | KMT2AMEN1CNR2POLBRAB9A | |
| SCHEMBL25893347 | 0.75 | KMT2A (0.48) | F10F2KMT2AMEN1NOD2 | |
| SCHEMBL7881984 | 0.74 | ALDH1A1 (0.50) | F10KMT2ACNR2ALDH1A1MTNR1A | |
| SCHEMBL6701629 | 0.74 | MCL1 (0.50) | F10KMT2AMEN1NOD2NOD1 | |
| SCHEMBL25893621 | 0.74 | F10 (0.57) | F10F2KMT2AMEN1NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |