Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837219 | 0.91 | HRH2 (0.40) | HRH2HRH1HPGDGPR119SMN1; SMN2 | |
| SCHEMBL7684482 | 0.90 | GPR119 (0.37) | HRH2HRH1ACHEGPR119SMN1; SMN2 | |
| SCHEMBL7676259 | 0.89 | GAA (0.37) | HRH2HRH1ACHEHRH3CHRM2 | |
| SCHEMBL7676252 | 0.89 | ACHE (0.35) | HRH2HRH1ACHEGPR119HRH3 | |
| SCHEMBL7682729 | 0.88 | ACHE (0.33) | HRH2HRH1ACHEGPR119HRH3 | |
| SCHEMBL7684757 | 0.87 | ACHE (0.37) | HRH2HRH1ACHEGPR119SMN1; SMN2 | |
| SCHEMBL7686984 | 0.85 | RAB9A (0.35) | ACHEGPR119SMN1; SMN2HRH3CHRM2 | |
| Hydrochloric Acid SCHEMBL7677602 | 0.85 | HRH2 (0.36) | HRH2HRH1ACHEHPGDSMN1; SMN2 | |
| SCHEMBL7677721 | 0.85 | GPR119 (0.36) | HRH2HRH1ACHEGPR119HRH3 | |
| SCHEMBL7680235 | 0.85 | ACHE (0.35) | ACHEGPR119SMN1; SMN2HRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1070712-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING ANTIPLATELET AGGREGATION EFFECT AND MEDICINAL USE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |