Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GFER | P55789 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978542 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL14563911 | 0.83 | GFER (0.69) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL7695241 | 0.79 | CA12 (0.63) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL7694205 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL7691811 | 0.75 | HPGD (0.53) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL13729062 | 0.74 | TDP1 (0.75) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL2316369 | 0.71 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL7072642 | 0.70 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL12410456 | 0.69 | GRM4 (0.47) | MEN1KMT2A | |
| SCHEMBL15452371 | 0.69 | TDP1 (0.76) | ALDH1A1KDM4EGFERHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066447-A1 | 4H-1,2,4-TRIAZOLE-3(2H)-THIONE DERATIVES AS SPHINGOMYELINASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |