Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14563911 | 0.80 | GFER (0.69) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL7687314 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL28543630 | 0.76 | KDM4E (0.79) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL8978622 | 0.73 | HPGD (0.79) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL7686847 | 0.72 | GAA (0.59) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL13977093 | 0.71 | GAA (0.74) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL7691829 | 0.71 | HPGD (0.91) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL10035358 | 0.71 | SMN1; SMN2 (0.69) | ALDH1A1KMT2AMEN1HPGDTSHR | |
| SCHEMBL28538869 | 0.70 | HPGD (0.77) | ALDH1A1KDM4EHPGDALOX15TSHR | |
| SCHEMBL10338918 | 0.69 | CYP19A1 (0.76) | ALDH1A1KMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066447-A1 | 4H-1,2,4-TRIAZOLE-3(2H)-THIONE DERATIVES AS SPHINGOMYELINASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |