MMP17 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3881504	1.00	11/20
SCHEMBL3881836	1.00	11/20
SCHEMBL3881841	1.00	11/20
SCHEMBL3882021	1.00	11/20
SCHEMBL3883225	1.00	11/20
SCHEMBL3883766	1.00	11/20
SCHEMBL3883897	1.00	11/20
SCHEMBL3996441	1.00	11/20
SCHEMBL3884431	0.86	11/20
SCHEMBL3998567	0.84	11/20
SCHEMBL3949306	0.82	11/20
SCHEMBL13901191	0.82	11/20
SCHEMBL3884523	0.81	11/20
SCHEMBL13957050	0.78	11/20
SCHEMBL3883065	0.75	11/20
SCHEMBL3880340	0.71	11/20
SCHEMBL3891961	0.68	11/20
SCHEMBL3886569	0.66	11/20
SCHEMBL3881204	0.65	11/20
SCHEMBL13957636	0.65	11/20

Clinical trials — most relevant to MMP17 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy	PHASE4	NOT_YET_RECRUITING
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
Interest of Dosage of Anti-PB230, Anti-PB180 and Cytokines for Monitoring of Patients Suffering From Bullous Pemphigoid	nan	COMPLETED
Cancer Fusion Hybrids and Desmoplasia	nan	UNKNOWN
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Salivary Markers in Periodontal Disorders	nan	COMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Characterizing Matrix Metalloproteinase-12 (MMP12) in Sputum	nan	RECRUITING
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease	nan	NOT_YET_RECRUITING
Matrix Metalloproteinase (MMP) in Heart Failure	nan	COMPLETED
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Macrophage Activation Markers in COVID-19 Patients	nan	COMPLETED
Evaluation of the Inflammatory Response in Post-operated Aortic Valve Replacement Patients.	nan	COMPLETED
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis	nan	RECRUITING
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Infection, Sepsis and Meningitis in Surinamese Neonates	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP17 binder may also engage these)

Protein	Name	Similarity
Q9R0S3	—	1.000	Q9R0S3 →
Q3U435	—	0.999	Q3U435 →
Q9H239	—	0.995	Q9H239 →
MMP11	Stromelysin-3	0.994	landscape →
Q499S5	—	0.994	Q499S5 →
Q02853	—	0.992	Q02853 →
MMP25	Matrix metalloproteinase-25	0.989	landscape →
Q99542	—	0.987	Q99542 →
Q9JHI0	—	0.987	Q9JHI0 →
MMP15	Matrix metalloproteinase-15	0.986	landscape →
Q96SM3	—	0.986	Q96SM3 →
Q9UK23	—	0.985	Q9UK23 →
ADAMTS7	A disintegrin and metalloproteinase with thrombospondin motifs 7	0.985	landscape →
O54732	—	0.985	O54732 →
O95754	—	0.984	O95754 →
Q8BYG9	—	0.984	Q8BYG9 →
Q6MG64	—	0.983	Q6MG64 →
Q91V24	—	0.983	Q91V24 →
Q9R0S2	—	0.983	Q9R0S2 →
O09127	—	0.983	O09127 →
Q99PW6	—	0.983	Q99PW6 →
Q03146	—	0.983	Q03146 →
EPHB4	Ephrin type-B receptor 4	0.982	landscape →
INSRR	Insulin receptor-related protein	0.982	landscape →
MMP24	Matrix metalloproteinase-24	0.982	landscape →
O08644	—	0.982	O08644 →
Q9Z0J7	—	0.982	Q9Z0J7 →
Q9Y334	—	0.982	Q9Y334 →
Q5R543	—	0.982	Q5R543 →
P55203	—	0.981	P55203 →