Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775525 | 0.89 | DRD3 (0.48) | DRD2DRD3DRD5SLC6A2SLC6A4 | |
| SCHEMBL6781480 | 0.86 | ADRA1D (0.43) | DRD2DRD3DRD5HTR7HTR1A | |
| SCHEMBL6769651 | 0.84 | DRD3 (0.48) | DRD2DRD3DRD5SLC6A2SLC6A4 | |
| SCHEMBL6780348 | 0.83 | DRD3 (0.46) | DRD2DRD3DRD5SLC6A2SLC6A4 | |
| SCHEMBL6773937 | 0.82 | DRD3 (0.45) | DRD2DRD3DRD5SLC6A2SLC6A4 | |
| SCHEMBL6774394 | 0.81 | DRD2 (0.51) | DRD2DRD3DRD5SLC6A2SLC6A4 | |
| SCHEMBL6774810 | 0.81 | DRD3 (0.44) | DRD2DRD3DRD5SIGMAR1HTR7 | |
| SCHEMBL6779876 | 0.79 | DRD3 (0.46) | DRD2DRD3DRD5SLC6A2SLC6A4 | |
| SCHEMBL6769645 | 0.79 | DRD3 (0.47) | DRD2DRD3DRD5SLC6A2SLC6A4 | |
| SCHEMBL6775746 | 0.79 | DRD3 (0.46) | DRD2DRD3DRD5SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020072515-A1 | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 2002-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072515-A1 | Pyrroloazepine derivatives | TPH2, HTR2A, HTR2C | DRD2 34/4885DRD3 165/4885DRD5 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.