Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683569 | 0.90 | SMN1; SMN2 (0.41) | TP53RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7687672 | 0.88 | SMN1; SMN2 (0.40) | TP53RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7689473 | 0.86 | SMN1; SMN2 (0.39) | GAATP53RECQLMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7680956 | 0.77 | POLB (0.36) | POLBGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7685489 | 0.76 | SMN1; SMN2 (0.43) | TP53RECQLSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7683958 | 0.74 | SMN1; SMN2 (0.42) | TP53RECQLKMT2ASMN1; SMN2MAPT | |
| SCHEMBL6163085 | 0.71 | HDAC1 (0.68) | TP53KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7683074 | 0.71 | TSHR (0.46) | TP53RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7687676 | 0.70 | SMN1; SMN2 (0.41) | TP53RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7683237 | 0.69 | SMN1; SMN2 (0.48) | TP53RECQLSMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |