Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 19/20 | 0.67 |
| ▸ | MMP2 | P08253 | 12/20 | 0.67 |
| ▸ | MMP1 | P03956 | 11/20 | 0.67 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767563 | 0.81 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6767568 | 0.81 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6769491 | 0.81 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL5919394 | 0.80 | MMP13 (0.64) | MMP13MMP2MMP1MMP3MMP8 | |
| SCHEMBL7299694 | 0.75 | MMP13 (0.62) | MMP13MMP2MMP1MMP3MMP8 | |
| SCHEMBL7360559 | 0.74 | MMP13 (0.62) | MMP13MMP2MMP1MMP3MMP8 | |
| SCHEMBL6764638 | 0.74 | MMP13 (0.67) | MMP13MMP2MMP1 | |
| SCHEMBL21967031 | 0.74 | MMP2 (0.51) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL6774922 | 0.74 | MMP13 (0.67) | MMP13MMP2MMP1 | |
| SCHEMBL5919644 | 0.74 | MMP1 (0.74) | MMP13MMP2MMP1MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | disclosed |