Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104020 | 0.80 | POLB (0.40) | POLBKMT2AALDH1A1DDAH1 | |
| SCHEMBL3590647 | 0.80 | POLB (0.40) | POLBKMT2AALDH1A1DDAH1 | |
| SCHEMBL10303857 | 0.79 | POLB (0.43) | POLBKMT2AALDH1A1DDAH1 | |
| SCHEMBL17121284 | 0.77 | POLB (0.41) | POLBKMT2AALDH1A1DDAH1 | |
| SCHEMBL7677400 | 0.76 | POLB (0.51) | POLBTAAR1GAAKMT2AALDH1A1 | |
| SCHEMBL13544590 | 0.71 | POLB (0.42) | POLBTAAR1KMT2AHSD17B10 | |
| SCHEMBL14850987 | 0.70 | POLB (0.35) | POLBTAAR1KMT2AALDH1A1DDAH1 | |
| SCHEMBL2524544 | 0.69 | — | — | |
| SCHEMBL13311598 | 0.69 | LMNA (0.52) | KMT2AALDH1A1 | |
| SCHEMBL7681618 | 0.68 | TDP1 (0.47) | POLBTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |