Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27692741 | 0.89 | DHODH (0.33) | KMT2AMEN1TP53ALDH1A1MAPT | |
| SCHEMBL7831772 | 0.86 | TSHR (0.31) | TP53MAPT | |
| SCHEMBL7687274 | 0.86 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL27674195 | 0.86 | DHODH (0.33) | HPGDALOX15DHODH | |
| SCHEMBL7833799 | 0.86 | KMT2A (0.38) | KMT2AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7831775 | 0.84 | GPR35 (0.47) | KMT2AALDH1A1MAPTNPC1HPGD | |
| SCHEMBL7665193 | 0.84 | — | — | |
| SCHEMBL7665197 | 0.84 | — | — | |
| SCHEMBL7680082 | 0.83 | CYP1A2 (0.33) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10695876 | 0.83 | BCAT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137929-A1 | 1 - (3-heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | INTELLECTUAL PROPERTY DEPARTMENT, BASF AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | US | disclosed |
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0563384-B1 | URACIL DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |
| US-5356863-A | Herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0563384-A1 | URACIL DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5154755-A | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0489480-A1 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-06-10 | — | — | EP | disclosed |
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137929-A1 | 1 - (3-heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | IMPDH1, GANC, DDT | KMT2A 2703/4885MEN1 3680/4885ROCK2 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.