Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685646 | 0.98 | NAAA (0.44) | NAAADGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL7689870 | 0.94 | ALDH1A1 (0.41) | NAAADGKAALDH1A1EPHX1ATM | |
| SCHEMBL7693487 | 0.92 | ALDH1A1 (0.50) | NAAADGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL1566316 | 0.92 | NAAA (0.50) | NAAAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL7689067 | 0.90 | NAAA (0.53) | NAAADGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL7693662 | 0.90 | NAAA (0.53) | NAAADGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL7693494 | 0.90 | NAAA (0.53) | NAAADGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL7691818 | 0.88 | NAAA (0.50) | NAAAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL7692519 | 0.86 | NAAA (0.53) | NAAADGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL7692970 | 0.85 | FAAH (0.41) | NAAADGKAALDH1A1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |