SCHEMBL7687969

SCHEMBL7687969

CCCCCNC(=O)OCCC

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.77
EPHX1 P07099 1/20 0.64
EPHX2 P34913 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11047247 0.98 ACHE (0.75) ACHEEPHX1EPHX2
SCHEMBL7685648 0.98 ACHE (0.75) ACHEEPHX1EPHX2
SCHEMBL7564851 0.96 ACHE (0.76) ACHEEPHX1EPHX2
SCHEMBL7689872 0.94 ACHE (0.88) ACHEEPHX1EPHX2
SCHEMBL1834619 0.94 ACHE (0.74) ACHEEPHX1EPHX2
SCHEMBL10447901 0.94 ACHE (0.74) ACHEEPHX1EPHX2
Iodide SCHEMBL25411377 0.92 ACHE (0.84) ACHEEPHX1
SCHEMBL1931371 0.92 ACHE (0.85) ACHEEPHX1EPHX2
SCHEMBL7693489 0.92 ACHE (0.78) ACHEEPHX1EPHX2
SCHEMBL13700167 0.92 ACHE (0.84) ACHEEPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220371973-A1 Method and Molecules MEDIMMUNE, LLC 2022-11-24 US disclosed
CN-109641835-B Method for producing carbamate 国立研究开发法人产业技术综合研究所 2021-07-20 CN disclosed
EP-3508473-B1 METHOD FOR PRODUCING CARBAMIC ACID ESTER AIST (JP) 2021-05-26 EP disclosed
US-10752579-B2 Production method of carbamic acid ester NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2020-08-25 US disclosed
EP-3508473-A1 METHOD FOR PRODUCING CARBAMIC ACID ESTER National Institute of Advanced Industrial Science and Technology (JP) 2019-07-10 EP disclosed
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-20 US disclosed
WO-2013071027-A1 MACROCYCLIC COMPOUNDS FOR INHIBITION OF INHIBITORS OF APOPTOSIS ENSEMBLE THERAPEUTICS (US) 2013-05-16 WO disclosed
US-8404650-B2 Methods of treating cancer with doxazolidine and prodrugs thereof THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-03-26 US disclosed
WO-2002000622-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220371973-A1 Method and Molecules VIP, LNPEP, IAPP ACHE 1623/4885EPHX1 3143/4885EPHX2 1644/4885
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER CA2, CA7, CA4 ACHE 195/4885EPHX1 4759/4885EPHX2 2372/4885
US-10752579-B2 Production method of carbamic acid ester CA2, CA7, CA4 ACHE 195/4885EPHX1 4759/4885EPHX2 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.