Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678959 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| Hydrochloric Acid SCHEMBL7688012 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| Hydrochloric Acid SCHEMBL7688010 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL16217087 | 0.77 | LMNA (0.69) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL7683237 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL7690465 | 0.74 | TP53 (0.46) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL31356800 | 0.73 | CLK4 (0.83) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL10778130 | 0.73 | CLK4 (0.83) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL14758473 | 0.72 | SMN1; SMN2 (0.79) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL7689656 | 0.72 | TP53 (0.49) | SMN1; SMN2ALDH1A1LMNAHTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |