Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7688208 | 0.96 | LSS (0.76) | LSS | |
| Fumaric Acid SCHEMBL7688205 | 0.96 | LSS (0.76) | LSS | |
| SCHEMBL7687928 | 0.85 | LSS (1.00) | LSSMEN1KMT2A | |
| SCHEMBL7681942 | 0.85 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL7681952 | 0.85 | LSS (0.64) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL7684101 | 0.83 | LSS (0.68) | LSS | |
| Fumaric Acid SCHEMBL7684105 | 0.83 | LSS (0.68) | LSS | |
| SCHEMBL3365759 | 0.75 | LSS (0.64) | LSSMEN1KMT2AMAOB | |
| SCHEMBL3362904 | 0.74 | LSS (0.74) | LSSMEN1KMT2A | |
| SCHEMBL22787145 | 0.72 | MAPT (0.50) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |