Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681737 | 0.88 | KDM4E (0.42) | KMT2AMEN1NOD2NOD1F10 | |
| SCHEMBL7684727 | 0.85 | F10 (0.46) | KMT2AMEN1NOD2NOD1F10 | |
| SCHEMBL7684512 | 0.84 | KMT2A (0.43) | KMT2AMEN1NOD2NOD1F10 | |
| SCHEMBL3960725 | 0.83 | KMT2A (0.54) | KMT2AMEN1NOD2NOD1F10 | |
| SCHEMBL7683854 | 0.82 | CACNA1B (0.39) | KMT2AL3MBTL1ALDH1A1KDM4ECACNA1B | |
| SCHEMBL7688134 | 0.79 | F10 (0.46) | KMT2AMEN1NOD2NOD1F10 | |
| SCHEMBL7679936 | 0.78 | EGLN1 (0.45) | KMT2AMEN1F10TDP1L3MBTL1 | |
| SCHEMBL7684301 | 0.78 | KMT2A (0.42) | KMT2AMEN1NOD2NOD1F10 | |
| SCHEMBL7684569 | 0.77 | KDM4E (0.42) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL7681745 | 0.75 | F10 (0.43) | KMT2AMEN1NOD2NOD1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |