Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684727 | 0.85 | F10 (0.46) | F10KMT2AALDH1A1NOD2NOD1 | |
| SCHEMBL7688134 | 0.85 | F10 (0.46) | F10KMT2AALDH1A1RAB9ANOD2 | |
| SCHEMBL3960725 | 0.85 | KMT2A (0.54) | F10CCR2KMT2AALDH1A1NOD2 | |
| SCHEMBL7684512 | 0.82 | KMT2A (0.43) | F10KMT2AALDH1A1ATMNOD2 | |
| SCHEMBL17060361 | 0.82 | CCR2 (0.57) | F10CCR2ITGA4ITGB7ALDH1A1 | |
| SCHEMBL7684301 | 0.80 | KMT2A (0.42) | F10PDE1CKMT2AALDH1A1RAB9A | |
| SCHEMBL18733288 | 0.79 | LTB4R (0.55) | F10KMT2ARAB9ANOD2NOD1 | |
| SCHEMBL7684569 | 0.77 | KDM4E (0.42) | F10KMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL17060318 | 0.77 | NOD2 (0.60) | F10CCR2KMT2AALDH1A1ATM | |
| SCHEMBL8480965 | 0.76 | CCR2 (0.49) | F10CCR2RAB9ANOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |