Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686579 | 0.85 | KDM4E (0.44) | KMT2AMEN1KDM4EATMCYP1A2 | |
| SCHEMBL3960725 | 0.84 | KMT2A (0.54) | KMT2AMEN1KDM4ECYP1A2POLB | |
| SCHEMBL7684301 | 0.81 | KMT2A (0.42) | KMT2AMEN1KDM4EL3MBTL1RAB9A | |
| SCHEMBL7684512 | 0.79 | KMT2A (0.43) | KMT2AMEN1KDM4EATML3MBTL1 | |
| SCHEMBL7684569 | 0.79 | KDM4E (0.42) | KMT2AMEN1KDM4ERAB9AALDH1A1 | |
| SCHEMBL7688134 | 0.78 | F10 (0.46) | KMT2AMEN1KDM4ERAB9AALDH1A1 | |
| SCHEMBL7688151 | 0.78 | KMT2A (0.38) | KMT2AMEN1KDM4EL3MBTL1RAB9A | |
| SCHEMBL7684727 | 0.78 | F10 (0.46) | KMT2AMEN1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL833455 | 0.75 | NOD2 (0.59) | KMT2AMEN1KDM4EATMCYP1A2 | |
| SCHEMBL7681745 | 0.75 | F10 (0.43) | KMT2AMEN1KDM4EATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |