Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684727 | 0.88 | F10 (0.46) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL3960725 | 0.88 | KMT2A (0.54) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL7688134 | 0.86 | F10 (0.46) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL7688151 | 0.84 | KMT2A (0.38) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL7684569 | 0.84 | KDM4E (0.42) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL7684301 | 0.82 | KMT2A (0.42) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL7681745 | 0.82 | F10 (0.43) | KMT2AMEN1F10ALDH1A1KDM4E | |
| SCHEMBL18733288 | 0.82 | LTB4R (0.55) | KMT2AMEN1F10SRD5A2NOD2 | |
| SCHEMBL7677561 | 0.81 | GPR35 (0.44) | ALDH1A1KDM4ELTB4RLTB4R2 | |
| SCHEMBL7679936 | 0.79 | EGLN1 (0.45) | KMT2AMEN1F10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |