Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 11/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695534 | 0.86 | ACP1 (0.45) | MKNK1TYRO3MALT1ALDH1A1HSD17B10 | |
| SCHEMBL7694476 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7695066 | 0.82 | MERTK (0.51) | TYRO3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL7688894 | 0.80 | SLC2A1 (0.50) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7690773 | 0.79 | HSD17B10 (0.43) | KDM4EALDH1A1HPGDHSD17B10IRAK4 | |
| SCHEMBL7695125 | 0.78 | KDM4E (0.51) | MKNK1ADORA1KDM4ELMNAHSD17B10 | |
| SCHEMBL7696545 | 0.75 | TSHR (0.45) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7696148 | 0.75 | CACNA2D1 (0.46) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7695093 | 0.73 | CYP1A2 (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5929386 | 0.70 | MALT1 (0.64) | ADORA1MALT1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076954-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |