Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694476 | 0.94 | ALDH1A1 (0.45) | ACP1USP2ALDH1A1TP53CYP1A2 | |
| SCHEMBL7695066 | 0.91 | MERTK (0.51) | ACP1ALDH1A1TP53GLAGAA | |
| SCHEMBL7688448 | 0.86 | MKNK1 (0.51) | ALDH1A1HSD17B10MKNK1MALT1TYRO3 | |
| SCHEMBL7690773 | 0.86 | HSD17B10 (0.43) | USP2ALDH1A1TP53CYP1A2GLA | |
| SCHEMBL7688894 | 0.85 | SLC2A1 (0.50) | HRH3USP2ALDH1A1TP53CYP1A2 | |
| SCHEMBL7695125 | 0.85 | KDM4E (0.51) | ACP1GAAHSD17B10MKNK1PARP1 | |
| SCHEMBL7688853 | 0.79 | MAPT (0.47) | ALDH1A1GAAMERTK | |
| SCHEMBL7696545 | 0.78 | TSHR (0.45) | USP2ALDH1A1TP53CYP1A2GLA | |
| SCHEMBL7696148 | 0.78 | CACNA2D1 (0.46) | USP2ALDH1A1TP53CYP1A2GLA | |
| SCHEMBL7695093 | 0.76 | CYP1A2 (0.46) | USP2ALDH1A1TP53CYP1A2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076954-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |