Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695534 | 0.85 | ACP1 (0.45) | MEN1KMT2AALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL7694476 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL7688448 | 0.80 | MKNK1 (0.51) | ALDH1A1HSD17B10HPGDKDM4ELMNA | |
| SCHEMBL7695066 | 0.79 | MERTK (0.51) | MEN1KMT2APOLBCSNK2A1FGFR1 | |
| SCHEMBL7690773 | 0.76 | HSD17B10 (0.43) | ALDH1A1HSD17B10HPGDKDM4ECYP3A4 | |
| SCHEMBL7695125 | 0.75 | KDM4E (0.51) | MEN1KMT2AHSD17B10KDM4ETSHR | |
| SCHEMBL7696545 | 0.75 | TSHR (0.45) | SLC2A1POLBFGFR1ALDH1A1HSD17B10 | |
| SCHEMBL7696148 | 0.74 | CACNA2D1 (0.46) | MEN1KMT2APOLBFGFR1ALDH1A1 | |
| SCHEMBL1184442 | 0.72 | KDR (0.52) | SLC2A1MEN1KMT2AFGFR1 | |
| SCHEMBL7695093 | 0.72 | CYP1A2 (0.46) | MEN1KMT2ACSNK2A1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076954-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |