Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | P4HB | P07237 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680007 | 0.81 | MAOA (0.52) | ADAMTS4GPR55MMP13MAPTMEN1 | |
| SCHEMBL7456800 | 0.80 | ALDH1A1 (0.47) | ADAMTS4GPR55MMP13MAPTMEN1 | |
| SCHEMBL7451641 | 0.77 | GPR55 (0.47) | F10ADAMTS4GPR55MMP13MEN1 | |
| SCHEMBL7446727 | 0.76 | F10 (0.57) | F10NAMPTPDCD1CD274 | |
| SCHEMBL7452363 | 0.75 | GPR55 (0.47) | F10ADAMTS4GPR55MMP13MAPT | |
| SCHEMBL891110 | 0.70 | GPR55 (0.52) | ADAMTS4GPR55MMP13MEN1KMT2A | |
| SCHEMBL6947906 | 0.69 | PDCD1 (0.54) | P4HBPDCD1CD274 | |
| SCHEMBL6947909 | 0.69 | PDCD1 (0.54) | P4HBPDCD1CD274 | |
| SCHEMBL890914 | 0.68 | GPR55 (0.47) | F10ADAMTS4GPR55MMP13MEN1 | |
| SCHEMBL7971670 | 0.68 | GPR55 (0.53) | GPR55MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1159264-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |