Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269141 | 0.89 | L3MBTL1 (0.45) | L3MBTL1MTNR1AMTNR1BCNR1MEN1 | |
| SCHEMBL8032126 | 0.88 | CNR1 (0.49) | L3MBTL1MTNR1AMTNR1BCNR1MEN1 | |
| SCHEMBL8032125 | 0.88 | CNR1 (0.49) | L3MBTL1MTNR1AMTNR1BCNR1MEN1 | |
| SCHEMBL8032242 | 0.88 | CNR1 (0.49) | L3MBTL1MTNR1AMTNR1BCNR1MEN1 | |
| SCHEMBL7680353 | 0.86 | F2 (0.42) | CNR1MEN1KMT2AF2F10 | |
| SCHEMBL7448150 | 0.85 | FFAR1 (0.37) | L3MBTL1MTNR1AMTNR1BCNR1MEN1 | |
| SCHEMBL19586903 | 0.85 | KMT2A (0.52) | MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL30947796 | 0.85 | ALDH1A1 (0.41) | CNR1MEN1KMT2AGAAF2 | |
| SCHEMBL6478160 | 0.85 | KCNA5 (0.44) | L3MBTL1MEN1KMT2AF2F10 | |
| SCHEMBL6478745 | 0.85 | ALDH1A1 (0.41) | CNR1MEN1KMT2AGAAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492392-B1 | INHIBITING TUMOR CELL PROLIFERATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| WO-2001085716-A1 | 2-PIPERIDONE COMPOUNDS FOR THE TREATMENT OF CANCER | KYOWA HAKKO KOGYO CO., LTD (JP) | 2001-11-15 | — | — | WO | disclosed |