Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269548 | 0.88 | F10 (0.44) | F2F10PRSS1CNR1ALDH1A1 | |
| SCHEMBL7688540 | 0.86 | L3MBTL1 (0.48) | F2F10PRSS1CNR1MEN1 | |
| SCHEMBL6478160 | 0.86 | KCNA5 (0.44) | F2F10PRSS1ALDH1A1CYP3A4 | |
| SCHEMBL6478745 | 0.86 | ALDH1A1 (0.41) | F2F10PRSS1CNR1ALDH1A1 | |
| SCHEMBL7688672 | 0.86 | MEN1 (0.49) | ALDH1A1CYP3A4CYP2C19HPGDLMNA | |
| SCHEMBL30947796 | 0.86 | ALDH1A1 (0.41) | F2F10PRSS1CNR1ALDH1A1 | |
| SCHEMBL7682611 | 0.86 | F2 (0.41) | F2F10PRSS1CNR1ALDH1A1 | |
| SCHEMBL698333 | 0.85 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HPGDKMT2A | |
| SCHEMBL29921355 | 0.85 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HPGDKMT2A | |
| SCHEMBL10642651 | 0.83 | ALDH1A1 (0.43) | CNR1ALDH1A1CYP3A4CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492392-B1 | INHIBITING TUMOR CELL PROLIFERATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| WO-2001085716-A1 | 2-PIPERIDONE COMPOUNDS FOR THE TREATMENT OF CANCER | KYOWA HAKKO KOGYO CO., LTD (JP) | 2001-11-15 | — | — | WO | disclosed |