Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | C5 | P01031 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14937721 | 0.78 | MAPT (0.50) | GAAMAPTKDM4EALDH1A1TSHR | |
| SCHEMBL22502146 | 0.78 | GAA (0.54) | SIGMAR1GAAMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL22502140 | 0.77 | GAA (0.57) | SIGMAR1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL5704614 | 0.77 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL2064577 | 0.76 | GAA (0.54) | GAAMAPTKDM4EALDH1A1TSHR | |
| SCHEMBL1157301 | 0.75 | PDE4A (0.56) | SIGMAR1PDE4A | |
| SCHEMBL7696638 | 0.75 | MCHR1 (0.54) | PDE4A | |
| SCHEMBL22502189 | 0.74 | MAPT (0.66) | GAAMAPTKDM4EALDH1A1TSHR | |
| SCHEMBL5649965 | 0.74 | KDM4E (0.56) | GAAMAPTKDM4EALDH1A1TSHR | |
| SCHEMBL7007168 | 0.73 | HTR1A (0.47) | SIGMAR1GAAMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002081447-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOTHIAZOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |