Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.56 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688645 | 0.85 | ELANE (0.54) | ELANECXCL8L3MBTL1NPSR1 | |
| SCHEMBL15867625 | 0.84 | ELANE (0.61) | ELANEL3MBTL1NPSR1 | |
| SCHEMBL11419918 | 0.83 | ELANE (0.59) | ELANENPSR1 | |
| SCHEMBL3150572 | 0.81 | ELANE (0.57) | ELANENPSR1 | |
| SCHEMBL16940033 | 0.81 | ELANE (0.57) | ELANENPSR1 | |
| SCHEMBL2381169 | 0.81 | CXCL8 (0.56) | ELANECXCL8L3MBTL1AKR1B1CHRM1 | |
| SCHEMBL3289983 | 0.80 | CXCL8 (0.59) | CXCL8L3MBTL1AKR1B1CHRM1TDP1 | |
| SCHEMBL23393760 | 0.80 | ELANE (0.56) | ELANENPSR1 | |
| SCHEMBL29607284 | 0.80 | ELANE (0.74) | ELANENPSR1 | |
| SCHEMBL8080533 | 0.79 | CXCL8 (0.58) | CXCL8L3MBTL1AKR1B1CHRM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380388-B1 | ACTIVITY AGAINST RETROVIRUSES SUCH AS HUMAN IMMUNODEFICIENCY VIRUS (HIV), HEPATITIS B VIRUS (HBV), AND HUMAN T-LYMPHOTROPIC VIRUS | BRANTFORD CHEMICALS INC. (CA) | 2002-04-30 | — | — | US | claimed |
| CN-109553610-B | Preparation method of emtricitabine isomer | 江西富祥药业股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| US-6380388-B1 | ACTIVITY AGAINST RETROVIRUSES SUCH AS HUMAN IMMUNODEFICIENCY VIRUS (HIV), HEPATITIS B VIRUS (HBV), AND HUMAN T-LYMPHOTROPIC VIRUS | BRANTFORD CHEMICALS INC. (CA) | 2002-04-30 | — | — | US | disclosed |