Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575280 | 0.86 | MAPK1 (0.49) | TSHRALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL6573305 | 0.86 | MEN1 (0.37) | TSHRTP53HPGDALDH1A1HSD17B10 | |
| SCHEMBL6573015 | 0.78 | CRHR1 (0.36) | TSHRTP53ALDH1A1HSD17B10NPC1 | |
| SCHEMBL6571969 | 0.77 | CRHR1 (0.42) | TSHRTP53HPGDALDH1A1HSD17B10 | |
| SCHEMBL6570965 | 0.76 | PLA2G7 (0.50) | TP53ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6574564 | 0.76 | CRHR1 (0.36) | TSHRTP53HPGDALDH1A1HSD17B10 | |
| SCHEMBL6573046 | 0.76 | HTR7 (0.44) | TSHRALDH1A1HSD17B10MAPK1MAPT | |
| SCHEMBL6574203 | 0.75 | CRHR1 (0.34) | TSHRTP53HCRTR1HCRTR2HPGD | |
| SCHEMBL6571815 | 0.74 | GAA (0.36) | TSHRALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL6571205 | 0.74 | CRHR1 (0.35) | TSHRTP53ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |