Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | RHOC | P08134 | 4/20 | 0.39 |
| ▸ | RHOA | P61586 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768895 | 1.00 | RORC (0.41) | RORCRHOCRHOAEPHX2SMN1; SMN2 | |
| SCHEMBL3979429 | 0.92 | RHOC (0.39) | RHOCRHOAEPHX2SMN1; SMN2TACR2 | |
| SCHEMBL3979427 | 0.92 | RHOC (0.39) | RHOCRHOAEPHX2SMN1; SMN2TACR2 | |
| SCHEMBL3985802 | 0.85 | TACR2 (0.36) | TACR2USP2CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL3985800 | 0.85 | TACR2 (0.36) | TACR2USP2CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL3979698 | 0.85 | TACR2 (0.42) | TACR2USP2CYP3A4HSD17B10CYP2D6 | |
| SCHEMBL3979699 | 0.85 | TACR2 (0.42) | TACR2USP2CYP3A4HSD17B10CYP2D6 | |
| SCHEMBL4631148 | 0.84 | TACR2 (0.46) | TACR2USP2CYP3A4HSD17B10CYP2D6 | |
| SCHEMBL3980108 | 0.83 | ALDH1A1 (0.37) | RHOASMN1; SMN2TACR2USP2CYP3A4 | |
| SCHEMBL3984404 | 0.83 | ALDH1A1 (0.37) | RHOASMN1; SMN2TACR2USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | RORC 1441/4885RHOC 3947/4885RHOA 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.