Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478257 | 0.92 | POLB (0.50) | OPRD1OPRK1ALDH1A1MAPK1MAPT | |
| SCHEMBL6539034 | 0.83 | MAOB (0.48) | ALDH1A1MAPK1MAPTGAAPOLB | |
| SCHEMBL6538633 | 0.83 | POLB (0.49) | OPRD1OPRK1ALDH1A1MAPK1MAPT | |
| SCHEMBL6538577 | 0.83 | POLB (0.49) | OPRD1OPRK1ALDH1A1MAPK1MAPT | |
| SCHEMBL7042715 | 0.82 | OPRD1 (0.40) | OPRD1OPRK1ALDH1A1MAPK1MAPT | |
| SCHEMBL7686428 | 0.81 | ADRB1 (0.49) | ALDH1A1MAPK1MAPTGAAPOLB | |
| SCHEMBL7043048 | 0.81 | POLB (0.43) | ALDH1A1MAPK1MAPTGAAPOLB | |
| SCHEMBL7040315 | 0.81 | POLB (0.49) | OPRD1ALDH1A1MAPK1MAPTGAA | |
| SCHEMBL7037724 | 0.80 | OPRD1 (0.38) | OPRD1OPRK1ALDH1A1MAPK1MAPT | |
| SCHEMBL6477918 | 0.80 | LPAR1 (0.39) | ALDH1A1MAPK1MAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |