SCHEMBL4950087

SCHEMBL4950087

N[C@H](C(=O)O)C(C=S)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.42
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
GLO1 Q04760 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4953782 1.00 SLC7A5 (0.42) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL7689414 0.76 SLC7A5 (0.43) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL29957453 0.69 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL25933046 0.69 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL468084 0.69 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL1007447 0.69 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL600021 0.69 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL6510366 0.69
SCHEMBL6429649 0.67 SLC7A5 (0.40) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL30011106 0.67 SLC7A5 (0.40) SLC7A5SLC1A3SLC1A2SLC1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442788-B2 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-10-28 US claimed
US-6872809-B2 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2005-03-29 US claimed
US-20030208050-A1 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-11-06 US claimed
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-08-28 US claimed
EP-1295892-A1 ANTISENSE MOLECULES AND METHOD OF CONTROLLING EXPRESSION OF GENE FUNCTION BY USING THE SAME Japan Science and Technology Corporation (JP) 2003-03-26 EP claimed
EP-1295891-A1 NUCLEOSIDE DERIVATIVES Japan Science and Technology Corporation (JP) 2003-03-26 EP claimed
US-7442788-B2 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-10-28 US disclosed
US-6872809-B2 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2005-03-29 US disclosed
US-6872809-B2 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2005-03-29 US disclosed
EP-1295891-A4 NUCLEOSIDE DERIVATIVES JAPAN SCIENCE & TECH CORP (JP) 2004-05-26 EP disclosed
US-20030208050-A1 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-11-06 US disclosed
US-20030208050-A1 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-11-06 US disclosed
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-08-28 US disclosed
EP-1295892-A1 ANTISENSE MOLECULES AND METHOD OF CONTROLLING EXPRESSION OF GENE FUNCTION BY USING THE SAME Japan Science and Technology Corporation (JP) 2003-03-26 EP disclosed
EP-1295891-A1 NUCLEOSIDE DERIVATIVES Japan Science and Technology Corporation (JP) 2003-03-26 EP disclosed
EP-1295891-A1 NUCLEOSIDE DERIVATIVES Japan Science and Technology Corporation (JP) 2003-03-26 EP disclosed
WO-2001096355-A1 NUCLEOSIDE DERIVATIVES JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2001-12-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same RNGTT, RNMT, UPF1 SLC7A5 1628/4885SLC1A3 891/4885SLC1A2 720/4885
US-20030208050-A1 Nucleoside derivatives RIMKLA, MTHFD1, AADAT SLC7A5 72/4885SLC1A3 70/4885SLC1A2 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.